imm-bcell-plasma-cause

Which autoimmune diseases depend on B cells or plasma cells?

Which autoimmune diseases improve when B cells or plasma cells are targeted, and what can identify the patients most likely to benefit? This project compares disease mechanisms with clinical intervention evidence, including response and nonresponse to rituximab.

Documents

• Working specification. Scope, evidence standards and the questions that remain to be answered.
• Evidence review and disease ranking. The initial synthesis, target comparison and approach to patient stratification.
• References. Recommended reviews first, followed by the studies supporting the synthesis and their verification status.

The related imm-biopsy project addresses whether blood and biopsy measurements represent B cells in other tissues.